you're right, only the define mini has the USB3.0 up top, but it's micro-ATX. The fractals are such great, silent cases, that I would probably get the R3 and just get a 3.5" usb front breakout (if you've got the space).

I've got the Define Mini with the stock fans, using the included fan controller. Running a Core i5-2500K at stock speeds and stock cooler, it's almost dead silent from a meter away. Thanks to the quiet case fans, the HDD bushings, and the bitumen coating, the stock CPU HSF is definitely the loudest ...