Regarding desktop computer use:
I recently contacted WD to inquire about an upgrade I am undertaking: more specifically replacing my Green (and Blue) drive(s) in the main workstation with a single Red one. I specified the chipset and CPU, and made clear that this was going into a desktop computer that also served files for two other workstations besides itself (acting like a NAS). The WD support reply was (with apology for delay removed):
[...]actually the WD Red is the best upgrade and it's specifically designed and tested for small office and home office.
I'm good with it if WD are. Looking forward to making the upgrade, as my 6400AAKS has a Power-On Hour count of 24,706. That's some 1,029 days altogether, which comes in at just under three years of constant running. Never had single a problem with it, but I feel it's time to retire the ol' warhorse.
(the 2 TB makes the most sense right now, I don't even have enough spare capacity to back up 3 TB of data)