Hi, if you wish to use the 280x then I would suggest an Arctic Cooling cooler, e.g. xtreme IV 280x
I've some experience with AC fans and have found them to be good, nice and smooth once slowed down. The massisve heatsink also gives you a fighting chance of keeping the card cool and quiet even under load.
You will want to choose a reference PCB card to be sure the cooler fits, as a bonus these are often the cheapest and the fact the factory cooler may not be very good is of no concern as you are changing it
You will also want to choose the case with this cooler in mind as it is long and wide and need enough room for it, and good case air flow to remove the heat the cooler takes from the video card and dumps in the case.
I would suggest connecting the new coolers fans to the video card so it can control the speed of them. Probably as the AC fans are only 2000 rpm full speed it's likely the card's BIOS will spin them at a quiet level at idle and increase when needed under load.
Under Windows utilities like MSI Afterburner (on any brand card) can alter the fan speed vs temperature curve, this can be helpful. Sometimes you can't set a low enough fan speed due to limits in the cards BIOS, in the past I've modded the BIOS of GT 610, GTX 260, HD5670 and current GTX 560Ti to get acceptable minimum fan speed.
Some people do prefer to set fan speed to the lowest level that provides enough cooling under extreme load and leave it fixed there, eg with fixed 7v or a "fanmate". This avoids any software control issues and any variation of sound that can be distracting. In case of a hot video card I would suggest the lowest level of acceptable cooling won't be silent, quiet for sure but enough that I would go with controlled fan speeds.
You will have to test it for yourself with your ears in your environment to know which is going to be best for you.
For the CPU just go with the standard 4770 or 4770k if you wish to overclock and can live with out VT-d (which might be important for your visualization needs)
Any half decent 120/140mm fan tower heatsink will keep a stock clock CPU cool and quiet, if overclocking lots then the bigger the better, either way look at the SPCR recommended list and pick one that's available from your preferred source at a price you like. E.G. Coolermaster Hyper 212 generally a sound and economical choice, I once used a Gelid Tranquillo on 3570k build and it was cheap, quiet and effective.