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 Post subject: No treatment for Ebola ... really?
PostPosted: Fri Jul 04, 2014 2:29 pm 
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Some of you may have read about the latest Ebola outbreak in West Africa. This time it's in cities, and difficult to control.

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The official information is that there is no treatment available, but my superficial investigation showed otherwise.
There is enough information available about FDA approved drugs with significant activity against the Ebola virus family
that salvage therapies could be tried, with one of the following: clomiphene, toremiphene, chloroquine, amodiaquine,
ketotifen, diphenoxylate, amiodarone, dronedarone, verapamil. I bolded the most promising ones (90% protection for mice with clomiphene).

I sent an e-mail to Amanpour at CNN about the possible use of clomiphene against Ebola. Maybe it won't end up in the junk / spam folder.
She interviewed Dr. Peter Piot, the discoverer of the Ebola virus, but there was no mention of possible therapies, just containment.


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 Post subject: Re: No treatment for Ebola ... really?
PostPosted: Fri Jul 04, 2014 4:38 pm 
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Location: Monterey Bay, CA
cities = people travel and infect others. Prevously, it was contained in remote villages. I've never heard of possible treatments - just isolate and let it literally die out.

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 Post subject: Re: No treatment for Ebola ... really?
PostPosted: Fri Jul 04, 2014 10:42 pm 
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When they say there is no treatment, that's because no drug treatment has been indicated for use in humans. It would need to be trialled in humans and with a disease that only ever comes in outbreaks, that's difficult. They would basically have to choose a sample of infected people to try the treatment on.

Ebola is very much a third world disease. It is believed to be carried by bats and can cross to humans and other animals. The bushmeat trade is believed to be one of the most likely points for infection. It is very infectious in the 3rd world as reuse of needles is common and hospitals can't afford all of the infection control measures. Dealing with the dead is also a major area of infection.

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 Post subject: Re: No treatment for Ebola ... really?
PostPosted: Sat Jul 05, 2014 2:21 am 
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It is not the only strange disease - this is a new one to me: chikungunya fever.

http://thinkprogress.org/climate/2014/07/03/3456524/chikungunya-spreads-throughout-caribbean/

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