No treatment for Ebola ... really?
Posted: Fri Jul 04, 2014 2:29 pm
Some of you may have read about the latest Ebola outbreak in West Africa. This time it's in cities, and difficult to control.
The official information is that there is no treatment available, but my superficial investigation showed otherwise.
There is enough information available about FDA approved drugs with significant activity against the Ebola virus family
that salvage therapies could be tried, with one of the following: clomiphene, toremiphene, chloroquine, amodiaquine,
ketotifen, diphenoxylate, amiodarone, dronedarone, verapamil. I bolded the most promising ones (90% protection for mice with clomiphene).
I sent an e-mail to Amanpour at CNN about the possible use of clomiphene against Ebola. Maybe it won't end up in the junk / spam folder.
She interviewed Dr. Peter Piot, the discoverer of the Ebola virus, but there was no mention of possible therapies, just containment.
The official information is that there is no treatment available, but my superficial investigation showed otherwise.
There is enough information available about FDA approved drugs with significant activity against the Ebola virus family
that salvage therapies could be tried, with one of the following: clomiphene, toremiphene, chloroquine, amodiaquine,
ketotifen, diphenoxylate, amiodarone, dronedarone, verapamil. I bolded the most promising ones (90% protection for mice with clomiphene).
I sent an e-mail to Amanpour at CNN about the possible use of clomiphene against Ebola. Maybe it won't end up in the junk / spam folder.
She interviewed Dr. Peter Piot, the discoverer of the Ebola virus, but there was no mention of possible therapies, just containment.