I've been using No Script, Ad Blocker Plus and Ghostery for a while. Yes, there is a learning curve where you have to decide whether or not to allow a site. I find that my browsing is about 95% repeat sites and 5% new sites. So, after a couple of days of training, only 5% or so new site training is needed. Given the ability to insert malicious content into flash, I really don't want it to play on sites I'm going to for the first time until I check out the site.
That's what more or less the same stuff that I use.
-FlashBlock (not really a privacy one, but still useful)
Plus a few other non-privacy related add ons.
NoScript is EXTREMELY painful to set up for the first time. It's incredible how many web sites rely on JS and do not work without it. But like you 95% of my browsing are the same sites that I visit daily so after first few weeks it's usually a breeze. I would never give it up. Occasionally you go on a website, and this is especially true of blogs, and they have stuff hotlinked from at least half a dozen other websites including double-click, ughhh...
Anyway, I googled for Ghostery add-on, this is something I haven't seen before. It says it can block tracking services like google analytics, but you already have the ability to block google analytics with no-script. So is Ghostery really that useful? Does it really add value over No-Script? Just wondering if I should add it to my list of essential privacy addons or not.
P.S. It's a sad state of affairs when you have to know/learn/use so much just in order to protect your privacy.